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Edexcel GCSE Biology 1BI0

Key Concepts in Biology

Topic overview Eukaryotic and prokaryotic cells Specialised cells and their adaptations Microscopes and magnification calculations Size, scale and units in cell biology Enzyme action and denaturation Factors affecting enzyme activity Enzymes in synthesis and digestion, and rate calculations Food tests and the energy in food Diffusion, osmosis and active transport Osmosis in potatoes and percentage change in mass

Cells and Control

Topic overview Mitosis and the cell cycle Why mitosis matters: growth, repair and cancer Growth, differentiation and percentile charts Stem cells and their use in medicine The structure and function of the brain Neurones, receptors and the reflex arc The structure and function of the eye Eye defects and how they are corrected

Genetics

Topic overview Asexual and sexual reproduction Meiosis and the formation of gametes DNA structure, genes and the genome Extracting DNA from fruit Mendel's work and the inheritance of blood groups Alleles, genotype and phenotype Monohybrid crosses and sex determination Probability and ratios from genetic crosses Causes of variation: genes and environment The Human Genome Project Genetic variation and the effects of mutation

Natural Selection and Genetic Modification

Topic overview Darwin, Wallace and the theory of evolution Natural selection and antibiotic resistance Fossil evidence for human evolution Stone tool evidence for human evolution The pentadactyl limb and the three domains Selective breeding Tissue culture Genetic engineering and modern agriculture Benefits and risks of GM organisms

Health, Disease and the Development of Medicines

Topic overview Health, disease and susceptibility Pathogens and common infections How pathogens spread, and the virus life cycle Sexually transmitted infections How plants defend themselves Physical barriers and chemical defences The immune system, immunisation and herd immunity Antibiotics and developing new medicines Aseptic technique in culturing microorganisms Testing antiseptics and antibiotics on bacterial cultures Lifestyle factors and non-communicable disease Treatments for cardiovascular disease

Plant Structures and Their Functions

Topic overview Photosynthesis as an endothermic reaction Limiting factors in photosynthesis Light intensity and the rate of photosynthesis Root hair cells, xylem and phloem Transpiration and translocation Leaf structure for photosynthesis and gas exchange Factors affecting the rate of transpiration Plant adaptations to extreme environments Plant hormones, phototropism and gravitropism

Animal Coordination, Control and Homeostasis

Topic overview Hormones, endocrine glands and homeostasis The menstrual cycle and its hormones Hormonal and barrier contraception Homeostasis and thermoregulation Controlling blood glucose, and type 1 diabetes Type 2 diabetes and body mass The urinary system and the production of urea The nephron, filtration and selective reabsorption Treating kidney failure: dialysis and transplants

Exchange and Transport in Animals

Topic overview Why multicellular organisms need exchange surfaces Alveoli and gas exchange Rate of diffusion and Fick's law The blood and its components Arteries, veins and capillaries The heart and the circulatory system Cellular respiration as an exothermic reaction Aerobic and anaerobic respiration compared Investigating the rate of respiration Cardiac output, stroke volume and heart rate

Ecosystems and Material Cycles

Topic overview Levels of organisation and interdependence Abiotic and biotic factors in a community Parasitism and mutualism Sampling with quadrats and transects Estimating population size from field data Energy transfer between trophic levels Human impact on ecosystems and biodiversity Food security The carbon cycle The water and nitrogen cycles Factors affecting the rate of decomposition Calculating the rate of decay

Genetics

DNA structure, genes and the genome

3 things to know
Paper 1

Overview

DNA as a double helix polymer of nucleotides made of a sugar, a phosphate and one of four bases, complementary base pairing held by weak hydrogen bonds, genes as sections of DNA coding for proteins, the genome, and why people with the same genes can differ.

What you need to know

Answer each one before you reveal it.

Your recallNot started

Key term

Describe the relationship between a gene, the genome and the proteins an organism makes.

Key term

What is the repeating unit from which the DNA polymer is built?

Key term

Describe the overall shape of a DNA molecule.

Questions from this subtopic

Each one with the model answer underneath.

1
What is the repeating unit from which the DNA polymer is built?
Model answer
DNA is built from repeating units called nucleotides.
2
Describe the overall shape of a DNA molecule.
Model answer
Two strands are coiled around each other to form a double helix.
3
Name the three parts that make up a single DNA nucleotide.
Model answer
A sugar, a phosphate group and one of four bases.
4
To which part of a nucleotide is the base attached?
Model answer
The base is attached to the sugar.
5
How many different bases are found in DNA?
Model answer
There are four different bases.
6
What type of bond holds a pair of bases together across the two strands?
Model answer
Weak hydrogen bonds hold each base pair together.

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Key Concepts in Biology

Cells and Control

Genetics

Natural Selection and Genetic Modification

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ANitrates cause an algal bloom that blocks the light.

BWater plants die and decay.

CThe decomposers use up the dissolved oxygen.

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A millimetre is 10⁻³ of a metre.

TrueFalse

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