Edexcel A-Level Biology B 9BI0
Biological Molecules
Cells, Viruses and Reproduction of Living Things
Classification and Biodiversity
Exchange and Transport
Energy for Biological Processes
Microbiology and Pathogens
Modern Genetics
Origins of Genetic Variation
Control Systems
Ecosystems
Control Systems
Effects of drugs on the nervous system
- 3 things to know
- Papers 2 and 3
Overview
Recall questions on agonists and antagonists, and on how named drugs alter synaptic transmission.
What you need to know
Answer each one before you reveal it.
If a neurone is treated with lidocaine, what happens when a stimulus is applied?
At what general level do drugs affect the nervous system?
Questions from this subtopic
Each one with the model answer underneath.
- 1
At what general level do drugs affect the nervous system?
Model answer
Drugs affect the nervous system by influencing synaptic transmission at various points in the process.
- 2
How does nicotine interact with acetylcholine receptors?
Model answer
Nicotine mimics the effects of acetylcholine by binding to acetylcholine receptors.
- 3
What type of drug action does nicotine exhibit at acetylcholine receptors?
Model answer
Nicotine acts as an agonist, stimulating the postsynaptic membrane in the same way as the natural neurotransmitter acetylcholine.
- 4
What specific ion channels does lidocaine target in neurones?
Model answer
Lidocaine blocks voltage-gated sodium ion channels.
- 5
Explain why blocking voltage-gated sodium ion channels prevents nerve impulse transmission.
Model answer
Blocking these channels prevents the depolarisation required for action potential generation and propagation.
- 6
If a neurone is treated with lidocaine, what happens when a stimulus is applied?
Model answer
No action potential is generated or propagated because the voltage-gated sodium ion channels are blocked, preventing depolarisation.
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