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Control Systems

Effects of drugs on the nervous system

  • 3 things to know
  • Papers 2 and 3

Overview

Recall questions on agonists and antagonists, and on how named drugs alter synaptic transmission.

What you need to know

Answer each one before you reveal it.

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Process

What type of drug action does nicotine exhibit at acetylcholine receptors?

Key term

If a neurone is treated with lidocaine, what happens when a stimulus is applied?

Key term

At what general level do drugs affect the nervous system?

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    At what general level do drugs affect the nervous system?

    Model answer

    Drugs affect the nervous system by influencing synaptic transmission at various points in the process.

  2. 2

    How does nicotine interact with acetylcholine receptors?

    Model answer

    Nicotine mimics the effects of acetylcholine by binding to acetylcholine receptors.

  3. 3

    What type of drug action does nicotine exhibit at acetylcholine receptors?

    Model answer

    Nicotine acts as an agonist, stimulating the postsynaptic membrane in the same way as the natural neurotransmitter acetylcholine.

  4. 4

    What specific ion channels does lidocaine target in neurones?

    Model answer

    Lidocaine blocks voltage-gated sodium ion channels.

  5. 5

    Explain why blocking voltage-gated sodium ion channels prevents nerve impulse transmission.

    Model answer

    Blocking these channels prevents the depolarisation required for action potential generation and propagation.

  6. 6

    If a neurone is treated with lidocaine, what happens when a stimulus is applied?

    Model answer

    No action potential is generated or propagated because the voltage-gated sodium ion channels are blocked, preventing depolarisation.

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