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Control Systems

Kidney structure and ultrafiltration

  • 5 things to know
  • Papers 2 and 3

Overview

Recall questions on the cortex, medulla and nephron, the glomerulus, Bowman's capsule and podocytes, how high hydrostatic pressure drives ultrafiltration through the filtration barrier, and deamination and urea formation in the liver.

What you need to know

Answer each one before you reveal it.

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Key term

What is the Bowman's capsule and where is it located within the nephron?

Key term

Explain how high hydrostatic pressure is generated in the glomerulus.

Key term

Define the renal pelvis and state its function.

Key term

What are the two main structural regions of the mammalian kidney, and what surrounds the entire organ?

Key term

Define deamination and state the products formed.

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    What are the two main structural regions of the mammalian kidney, and what surrounds the entire organ?

    Model answer

    The kidney has an outer cortex and inner medulla, and is surrounded by a fibrous capsule.

  2. 2

    What is the collecting duct and what is its role in the nephron?

    Model answer

    The collecting duct is the final tubular section of the nephron that receives filtrate from multiple nephrons and carries urine towards the renal pelvis.

  3. 3

    What is the glomerulus and what process occurs there?

    Model answer

    The glomerulus is a knot of capillaries surrounded by the Bowman's capsule where ultrafiltration occurs.

  4. 4

    What is the Bowman's capsule and where is it located within the nephron?

    Model answer

    The Bowman's capsule is the cup-shaped structure at the beginning of the nephron that surrounds the glomerulus and receives the filtrate.

  5. 5

    Describe the structure of the Bowman's capsule and identify the specialised cells on its inner layer.

    Model answer

    The Bowman's capsule has a cup-shaped structure with an inner layer of podocytes that wrap around the glomerular capillaries.

  6. 6

    How do podocytes contribute to the filtration process in the kidney?

    Model answer

    Podocytes have foot processes with filtration slits between them that allow small molecules to pass through into the Bowman's capsule.

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