Edexcel A-Level Psychology 9PS0
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Clinical Psychology
Developmental psychology in clinical psychology
- 3 things to know
- Papers 2 and 3
Overview
Recall questions on genetic and biochemical explanations of schizophrenia, twin and adoption evidence, and the typical age of onset.
What you need to know
Answer each one before you reveal it.
What evidence suggests a genetic component to schizophrenia?
What is the approximate monozygotic twin concordance rate for schizophrenia?
Questions from this subtopic
Each one with the model answer underneath.
- 1
What evidence suggests a genetic component to schizophrenia?
Model answer
Concordance is far higher in monozygotic than dizygotic twins, and risk rises with closeness of biological relationship regardless of upbringing.
- 2
What is the approximate monozygotic twin concordance rate for schizophrenia?
Model answer
Around 40 to 50 per cent.
- 3
Why does a concordance rate below 100 per cent matter?
Model answer
Because identical twins share all their genes, so anything short of complete concordance shows environment must also contribute.
- 4
What is the dopamine hypothesis of schizophrenia?
Model answer
That the positive symptoms arise from excess dopamine activity, particularly at D2 receptors in the mesolimbic pathway.
- 5
What evidence supports the dopamine hypothesis?
Model answer
Antipsychotics that block D2 receptors reduce positive symptoms, while amphetamines that raise dopamine can produce psychotic symptoms.
- 6
How does the revised dopamine hypothesis account for negative symptoms?
Model answer
By proposing low dopamine activity in the prefrontal cortex alongside excess in subcortical pathways.
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