Edexcel A-Level Psychology 9PS0
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Health Psychology
Biological explanations of drug addiction
- 4 things to know
- Papers 2 and 3
Overview
Recall questions on drugs and the mesolimbic reward pathway, how alcohol, heroin and nicotine each act on GABA, glutamate, opioid and nicotinic receptors, and how neuroadaptation produces tolerance and withdrawal for each.
What you need to know
Answer each one before you reveal it.
What is the consequence of heroin inhibiting GABA interneurons for dopamine release?
Why do heroin users require increasing doses over time?
What causes withdrawal symptoms in heroin addiction?
Questions from this subtopic
Each one with the model answer underneath.
- 1
According to the biological explanation, how do drugs initially affect the brain to promote addiction?
Model answer
Drugs alter neurotransmitter activity in the brain.
- 2
Which brain structure is particularly associated with dopamine release during drug use?
Model answer
The nucleus accumbens.
- 3
What brain system is activated by drugs that contributes to the development of addiction?
Model answer
The mesolimbic reward pathways.
- 4
How does activation of reward pathways contribute to addiction according to the biological explanation?
Model answer
It reinforces drug-taking behaviour, making the individual more likely to repeat drug use.
- 5
How might genetic factors predispose individuals to addiction?
Model answer
Through inherited variations in neurotransmitter systems and metabolic enzymes that affect drug responses.
- 6
Which receptor type does alcohol bind to in order to enhance inhibitory neurotransmission?
Model answer
GABA-A receptors
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