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Clinical Psychology

Explanations of schizophrenia

  • 4 things to know
  • Papers 2 and 3

Overview

Recall questions on the dopamine hypothesis and its drug evidence, twin concordance, enlarged ventricles and reduced prefrontal and temporal volume, expressed emotion, the cognitive and social causation explanations, glutamate dysfunction and double-bind theory.

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Key term

How do dopamine agonists provide evidence for the dopamine hypothesis of schizophrenia?

Key term

What do twin studies suggest about the role of genetics in schizophrenia?

Key term

What pharmacological evidence supports a role for glutamate in schizophrenia?

Who and when

According to the dopamine hypothesis, which brain pathway shows excessive dopamine activity in schizophrenia?

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    According to the dopamine hypothesis, which brain pathway shows excessive dopamine activity in schizophrenia?

    Model answer

    The mesolimbic pathway.

  2. 2

    How do dopamine agonists provide evidence for the dopamine hypothesis of schizophrenia?

    Model answer

    Dopamine agonists can induce psychotic symptoms, suggesting that excessive dopamine activity is involved in schizophrenia.

  3. 3

    How do antipsychotic medications support the dopamine hypothesis?

    Model answer

    Antipsychotics work by blocking dopamine D2 receptors, reducing symptoms and supporting the role of excess dopamine in schizophrenia.

  4. 4

    What are neurotransmitters?

    Model answer

    Chemical messengers that transmit signals across synapses between neurons; their dysfunction can contribute to mental disorders.

  5. 5

    What concordance rates for schizophrenia are found in monozygotic versus dizygotic twins?

    Model answer

    Approximately 48% concordance in monozygotic twins compared to 17% in dizygotic twins.

  6. 6

    What do twin studies suggest about the role of genetics in schizophrenia?

    Model answer

    Higher concordance rates in monozygotic twins compared to dizygotic twins support inherited vulnerability to schizophrenia.

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