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Clinical Psychology
Explanations of schizophrenia
- 4 things to know
- Papers 2 and 3
Overview
Recall questions on the dopamine hypothesis and its drug evidence, twin concordance, enlarged ventricles and reduced prefrontal and temporal volume, expressed emotion, the cognitive and social causation explanations, glutamate dysfunction and double-bind theory.
What you need to know
Answer each one before you reveal it.
What do twin studies suggest about the role of genetics in schizophrenia?
What pharmacological evidence supports a role for glutamate in schizophrenia?
According to the dopamine hypothesis, which brain pathway shows excessive dopamine activity in schizophrenia?
Questions from this subtopic
Each one with the model answer underneath.
- 1
According to the dopamine hypothesis, which brain pathway shows excessive dopamine activity in schizophrenia?
Model answer
The mesolimbic pathway.
- 2
How do dopamine agonists provide evidence for the dopamine hypothesis of schizophrenia?
Model answer
Dopamine agonists can induce psychotic symptoms, suggesting that excessive dopamine activity is involved in schizophrenia.
- 3
How do antipsychotic medications support the dopamine hypothesis?
Model answer
Antipsychotics work by blocking dopamine D2 receptors, reducing symptoms and supporting the role of excess dopamine in schizophrenia.
- 4
What are neurotransmitters?
Model answer
Chemical messengers that transmit signals across synapses between neurons; their dysfunction can contribute to mental disorders.
- 5
What concordance rates for schizophrenia are found in monozygotic versus dizygotic twins?
Model answer
Approximately 48% concordance in monozygotic twins compared to 17% in dizygotic twins.
- 6
What do twin studies suggest about the role of genetics in schizophrenia?
Model answer
Higher concordance rates in monozygotic twins compared to dizygotic twins support inherited vulnerability to schizophrenia.
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