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Medical Physics

Half-life

  • 3 things to know
  • Paper 3, section B

Overview

Physical, biological and effective half-life, and the formula relating them.

What you need to know

Answer each one before you reveal it.

Your recallNot started
Numbers

What determines physical half-life, and what processes give the biological one?

Numbers

How does effective half-life compare with the other two, and what formula links them?

Numbers

What is the formula for effective half-life, and what do its terms represent?

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    What is meant by the physical half-life of a radioactive isotope?

    Model answer

    The time taken for half the radioactive nuclei in a sample to decay, determined solely by the nuclear properties of the isotope.

  2. 2

    What factor determines the physical half-life of a radioisotope?

    Model answer

    The nuclear properties of the isotope itself; it is independent of external conditions.

  3. 3

    Define biological half-life.

    Model answer

    The time taken for half of a substance to be removed from the body by biological processes such as metabolism and excretion.

  4. 4

    Which processes contribute to the biological half-life of a substance in the body?

    Model answer

    Metabolism and excretion.

  5. 5

    What is the effective half-life of a radioactive substance in the body?

    Model answer

    The time taken for the activity of a radioactive substance in the body to fall to half its original value, accounting for both radioactive decay and biological removal.

  6. 6

    Why does effective half-life account for two separate processes?

    Model answer

    Because both radioactive decay (physical) and biological removal occur simultaneously, each contributing to the reduction in activity.

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