OCR A-Level Biology B H422
The Developing Cell: Cell Division and Cell Differentiation
The Developing Individual: Meiosis, Growth and Development
The Development of Species: Evolution and Classification
Cells and Microscopy
Water and Its Importance in Plants and Animals
Proteins and Enzymes
Nucleic Acids
Patterns of Inheritance
Population Genetics and Epigenetics
Gene Technologies
The Principles and Importance of Homeostasis
The Hormonal Control of Blood Glucose and the Management of Diabetes
Kidney Functions and Malfunctions
The Cellular Basis of Cancer and Treatment
Respiratory Diseases and Treatment
Cellular Respiration
Metabolism and Exercise
Pathogenic Microorganisms
The Immune System
Controlling Communicable Diseases
Photosynthesis, Food Production and Management of the Environment
The Impact of Population Increase
Planning and Implementing Practical Work
Analysing and Evaluating Practical Results
Practical Skills, Apparatus and Techniques
Fertility and Assisted Reproduction
The Effects of Ageing on the Reproductive System
Plant Reproduction
The Nervous System and the Identification and Consequences of Damage
Monitoring Visual Function
The Effect of Ageing on the Nervous System
The Heart and Monitoring Heart Function
Transport Systems in Mammals
Gas Exchange in Mammals and Plants
Controlling Communicable Diseases
- 4 subtopics
- 12 things to know
- Components 01, 02 and 03
What Controlling Communicable Diseases covers
Controlling Communicable Diseases is examined in all three written papers — the specification states that Components 01, 02 and 03 can each assess content from any of the five modules, so nothing is confined to one paper. It covers vaccination and vaccination programmes, problems and ethics of vaccine development and use, antibiotics and antibiotic resistance and investigating antibiotics, disinfectants and hygiene.
Where it is assessed
Components 01, 02 and 03
Every module can be assessed on any of the three papers.
Check the OCR specification ↗The 4 subtopics
Each one has its own page.
- Vaccination and vaccination programmesRecall questions on how vaccines produce memory cells, live attenuated vaccines for measles and tuberculosis and their drawbacks, vaccines of killed pathogens and fragments, booster doses, herd immunity, who depends on it, and what happens when coverage falls.Open →
- Problems and ethics of vaccine development and useRecall questions on antigenic variability and the yearly influenza vaccine, antigenic shift and pandemics, why no HIV vaccine exists, live vaccines reverting to virulence, the cold chain and rural distribution, protein deficiency, and the HPV vaccine and the ethical objections to it.Open →
- Antibiotics and antibiotic resistanceRecall questions on how different antibiotics attack a bacterium, why viruses are unaffected, the cell differences that make selective toxicity possible, how resistance spreads, and the hospital-acquired strains.Open →
- Investigating antibiotics, disinfectants and hygieneRecall questions on testing antibiotics with discs on a bacterial lawn, measuring zones of inhibition and calculating their area, controls and control variables, penicillin against Gram-positive and Gram-negative bacteria, bacteriostatic and bactericidal antibiotics, disinfectants and antiseptics, and handwashing with soap.Open →
What you need to know
Answer each one before you reveal it.
Explain why a very infectious disease needs high vaccination coverage, and what follows when coverage drops.
Distinguish the two classes of antibiotic action and describe how you would find out which one you have.
Explain how a clear zone appears around an antibiotic disc and why its diameter does not rank two antibiotics.
How is the effect of an antibiotic on a bacterium investigated using agar plates?
Why does the influenza vaccine have to be reformulated every year?
What is a vaccine?
What is antigenic shift, and why does it cause pandemics?
What is an antibiotic?
Name two diseases that are vaccinated against using a live attenuated vaccine.
Why is the mutation rate of HIV so high?
Why do antibiotics have no effect on a viral infection?
Take Controlling Communicable Diseases further
The same content, four other ways.
Commonly confused
Pairs that lose marks when they are blurred together.
Bacteriostatic vs Bactericidal
Bacteriostatic: stopping bacteria reproducing without killing them, so the immune system is left to clear the cells that survive. Bactericidal: killing the bacteria outright, so no living cells remain to be cleared.
Disinfectant vs Antiseptic
Disinfectant: a chemical strong enough to kill microorganisms on non-living surfaces and equipment, but too harsh to put on the body. Antiseptic: a chemical mild enough to be applied to living skin or an open wound without damaging the tissue.
Antigenic drift vs Antigenic shift
Antigenic drift: the gradual accumulation of mutations that alters a virus's surface proteins a little each year, causing seasonal epidemics. Antigenic shift: a sudden exchange of genetic segments between two strains inside one host, creating a subtype nobody is immune to and so causing a pandemic.
Questions from this topic
Each one with the model answer underneath.
- 1
What is a vaccine?
Model answer
A vaccine is a preparation containing antigens from a pathogen in a form that produces immunity without causing the disease.
- 2
On what principle does vaccination work?
Model answer
The vaccine provokes a primary immune response that produces plasma cells and, above all, memory cells, so that a later natural infection meets a rapid secondary response and is destroyed before symptoms develop.
- 3
What is a live attenuated vaccine?
Model answer
It is a vaccine containing a weakened strain of the pathogen that can still reproduce inside the body but has lost the ability to cause the disease.
- 4
Name two diseases that are vaccinated against using a live attenuated vaccine.
Model answer
Measles and tuberculosis.
- 5
Why does a live vaccine usually give stronger and longer-lasting protection than a killed one?
Model answer
The attenuated pathogen reproduces inside the body, so its antigens are presented in increasing amounts over a much longer period and a far larger clone of memory cells is produced.
- 6
State one disadvantage of a live attenuated vaccine.
Model answer
It cannot safely be given to people whose immune systems are suppressed, because even a weakened pathogen may cause disease in them.
What is inside Levo
Six ways to work the same material.
Controlling Communicable Diseases revision questions
- What does Controlling Communicable Diseases cover in OCR A-Level Biology B?
- 4 subtopics: vaccination and vaccination programmes, problems and ethics of vaccine development and use, antibiotics and antibiotic resistance and investigating antibiotics, disinfectants and hygiene. Each one has its own page with questions and model answers.
- How is Controlling Communicable Diseases organised?
- By the OCR H422 specification, subtopic by subtopic, so it matches the order you are taught it in.
Every question in Controlling Communicable Diseases, on a schedule.
Attempt a question from memory, write the correct version, then attempt it again. Levo records the jump between your first attempt and your last, and brings each question back on the day you are due to forget it.
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