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Variation and Evolution

The Hardy-Weinberg principle

  • 3 things to know
  • Component 2

Overview

Hardy-Weinberg equation relating the two allele frequencies, hardy-Weinberg equation relating the genotype frequencies and four conditions under which the Hardy-Weinberg principle applies.

What you need to know

Answer each one before you reveal it.

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Key term

What does the Hardy-Weinberg principle state?

Key term

State the Hardy-Weinberg equation relating the two allele frequencies.

Key term

State the Hardy-Weinberg equation relating the genotype frequencies.

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    What does the Hardy-Weinberg principle state?

    Model answer

    It states that the allele frequencies of a population remain constant from one generation to the next, provided that certain conditions are met.

  2. 2

    State the Hardy-Weinberg equation relating the two allele frequencies.

    Model answer

    p + q = 1, in which p is the frequency of the dominant allele and q that of the recessive allele.

  3. 3

    State the Hardy-Weinberg equation relating the genotype frequencies.

    Model answer

    p² + 2pq + q² = 1.

  4. 4

    What does each term of the genotype equation represent?

    Model answer

    p² is the proportion of homozygous dominant individuals, 2pq the proportion of heterozygotes, and q² the proportion of homozygous recessives.

  5. 5

    Why does the frequency of the recessive phenotype give q² directly?

    Model answer

    Only individuals homozygous for the recessive allele show that phenotype, so their proportion is the square of the recessive allele frequency.

  6. 6

    One person in 400 shows a recessive condition. Calculate the frequency of the recessive allele.

    Model answer

    q² is 1 divided by 400, which is 0.0025, so q is the square root of 0.0025, which is 0.05.

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