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Cancer

Lifestyle factors in cancer risk

  • 3 things to know
  • AS 2

Overview

Body fat, physical activity, alcohol, breastfeeding, smoking, sun exposure and sunbeds as influences on cancer risk.

What you need to know

Answer each one before you reveal it.

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Numbers

How many cancers did the World Cancer Research Fund link to excess body fat in 2018?

Key term

Explain how excess body fat can raise the risk of breast cancer after the menopause.

Key term

Apart from raising oestrogen, how does excess body fat promote cancer growth?

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    How many cancers did the World Cancer Research Fund link to excess body fat in 2018?

    Model answer

    The World Cancer Research Fund linked excess body fat to twelve cancers in 2018. Examples include bowel, post-menopausal breast, womb, kidney, liver and oesophageal cancer.

  2. 2

    Explain how excess body fat can raise the risk of breast cancer after the menopause.

    Model answer

    Fat tissue is the main source of oestrogen once the ovaries stop producing it after the menopause. More body fat means more oestrogen, which stimulates breast cells to divide.

  3. 3

    Apart from raising oestrogen, how does excess body fat promote cancer growth?

    Model answer

    Excess body fat raises insulin and insulin-like growth factor, which stimulate cells to divide. Fat tissue also causes chronic low-grade inflammation that can damage DNA.

  4. 4

    Which cancers does regular physical activity help protect against?

    Model answer

    Regular physical activity lowers the risk of bowel cancer. Activity also lowers the risk of breast cancer after the menopause and cancer of the womb.

  5. 5

    Explain how physical activity may reduce bowel cancer risk.

    Model answer

    Activity speeds the movement of waste through the gut, cutting the contact time between carcinogens and the bowel lining. Activity also lowers insulin levels and helps control body fat.

  6. 6

    Which cancers are linked to drinking alcohol?

    Model answer

    Alcohol raises the risk of seven cancers: mouth, pharynx, larynx, oesophagus, breast, bowel and liver.

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