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Cardiovascular Disease

Smoking, inactivity, alcohol, obesity and Type 2 diabetes

  • 3 things to know
  • AS 2

Overview

How smoking, inactivity and sitting, excess alcohol, obesity and Type 2 diabetes damage the heart and blood vessels.

What you need to know

Answer each one before you reveal it.

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Key term

How does smoking damage the lining of the arteries?

Key term

How does carbon monoxide in cigarette smoke affect the cardiovascular system?

Key term

How does nicotine affect the heart and blood vessels?

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    How does smoking damage the lining of the arteries?

    Model answer

    Tobacco smoke contains free radicals and toxic chemicals that injure the endothelium. Damaged endothelium lets LDL enter the artery wall and starts plaque formation.

  2. 2

    How does carbon monoxide in cigarette smoke affect the cardiovascular system?

    Model answer

    Carbon monoxide binds to haemoglobin more readily than oxygen, reducing the blood's oxygen-carrying capacity. The heart must work harder to supply the tissues with oxygen.

  3. 3

    How does nicotine affect the heart and blood vessels?

    Model answer

    Nicotine stimulates adrenaline release, raising heart rate and blood pressure. Nicotine also narrows blood vessels.

  4. 4

    How does smoking increase the risk of a blood clot blocking an artery?

    Model answer

    Chemicals in smoke make platelets stickier and raise levels of the clotting protein fibrinogen. A clot is then more likely to form on a plaque and block an artery.

  5. 5

    Explain how reduced physical activity contributes to the development of CVD.

    Model answer

    Inactivity allows blood pressure, LDL and triglycerides to rise and HDL to fall. An inactive person also gains weight more easily and becomes less sensitive to insulin.

  6. 6

    Why is long sitting time a risk factor for CVD even in people who exercise?

    Model answer

    Long periods of sitting reduce the muscle activity that helps clear fat and glucose from the blood. High sitting time is linked to CVD independently of exercise.

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Nicotine also blood vessels.
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