Eduqas A-Level Psychology A290QS
Biological Approach
Psychodynamic Approach
Behaviourist Approach
Cognitive Approach
Positive Approach
Comparing the Five Approaches
Core Studies in Social and Developmental Psychology
Planning Psychological Research
Data Handling, Statistics and Mathematical Skills
Evaluating and Validating Research
Personal Investigations and Novel Research Scenarios
Addictive BehavioursAddictive
Autistic Spectrum BehavioursAutistic spectrum
Bullying BehavioursBullying
Criminal BehavioursCriminal
SchizophreniaSchizophrenia
StressStress
Controversies in Psychology
Addictive Behaviours
Methods of modifying the behaviour: Agonist and antagonist substitution
- 3 things to know
- Component 3 Applications
Overview
Recall questions on Agonist substitution and antagonist substitution.
What you need to know
Answer each one before you reveal it.
Name the agonist most widely used in opiate dependence and describe how it is given.
How does nicotine replacement therapy follow the agonist principle?
Questions from this subtopic
Each one with the model answer underneath.
- 1
Define an agonist.
Model answer
A substance that binds to a receptor and activates it, producing the same kind of effect as the natural transmitter or the drug of dependence.
- 2
Define an antagonist.
Model answer
A substance that binds to a receptor and blocks it without activating it, so the drug of dependence can no longer produce its effect.
- 3
What is agonist substitution?
Model answer
Replacing the drug of dependence with a longer-acting, safer drug acting at the same receptors, given in a controlled dose so that withdrawal and craving are prevented without the peaks of intoxication.
- 4
Name the agonist most widely used in opiate dependence and describe how it is given.
Model answer
Methadone, taken orally as a single measured daily dose, usually supervised at a pharmacy.
- 5
What is buprenorphine, and why is it regarded as safer than methadone in overdose?
Model answer
It is a partial agonist at opioid receptors whose depressant effect on breathing reaches a ceiling, so increasing the dose does not go on suppressing respiration indefinitely.
- 6
How does nicotine replacement therapy follow the agonist principle?
Model answer
Patches, gum and lozenges deliver nicotine, an agonist at nicotinic receptors, slowly and without tobacco smoke, so withdrawal is eased while the smoking behaviour itself is dropped.
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