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Schizophrenia

Biological explanations for schizophrenia

  • 4 things to know
  • Paper 3

Overview

Family and twin study evidence for a genetic basis, neural correlates, and the dopamine hypothesis with its evaluation.

What you need to know

Answer each one before you reveal it.

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Key term

How do family and twin studies support a genetic explanation?

Key term

What are neural correlates of schizophrenia?

Key term

What does the dopamine hypothesis claim about schizophrenia?

Evaluation

Evaluate the dopamine hypothesis as an explanation of schizophrenia.

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    What does the genetic explanation for schizophrenia propose about how the disorder is transmitted?

    Model answer

    It proposes that schizophrenia is inherited through genes passed from parents to offspring.

  2. 2

    What do family studies reveal about the relationship between genetic relatedness and schizophrenia risk?

    Model answer

    The risk of developing schizophrenia increases with genetic relatedness to an affected individual.

  3. 3

    How do twin studies assess the genetic contribution to schizophrenia?

    Model answer

    They compare concordance rates between monozygotic twins (sharing 100% of genes) and dizygotic twins (sharing approximately 50% of genes).

  4. 4

    What do concordance rates in twin studies suggest about the genetic component of schizophrenia?

    Model answer

    Concordance rates are higher in monozygotic twins than dizygotic twins, suggesting a genetic component to the disorder.

  5. 5

    Why do concordance rates in monozygotic twins provide evidence that genetics alone cannot fully explain schizophrenia?

    Model answer

    Concordance rates for monozygotic twins are not 100%, indicating that other factors beyond genetics must be involved.

  6. 6

    What are neural correlates in relation to schizophrenia?

    Model answer

    Measurable brain abnormalities associated with schizophrenia, including structural and functional differences.

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