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Health and Well-Being

Inherited conditions: cystic fibrosis and Huntington's disease

  • 3 things to know
  • AS 3

Overview

Carrier of cystic fibrosis and three effects of Huntington's disease on a person.

What you need to know

Answer each one before you reveal it.

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Key term

What pattern of inheritance does cystic fibrosis follow?

Key term

Which gene is faulty in cystic fibrosis?

Key term

If both parents carry the cystic fibrosis gene, what is the chance in each pregnancy that the child will have the condition?

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    What pattern of inheritance does cystic fibrosis follow?

    Model answer

    Cystic fibrosis follows an autosomal recessive pattern, so a child must inherit a faulty copy of the gene from both parents to have the condition.

  2. 2

    Which gene is faulty in cystic fibrosis?

    Model answer

    The CFTR gene on chromosome 7 is faulty in cystic fibrosis.

  3. 3

    If both parents carry the cystic fibrosis gene, what is the chance in each pregnancy that the child will have the condition?

    Model answer

    The chance is one in four, or 25%, in each pregnancy when both parents are carriers.

  4. 4

    What is a carrier of cystic fibrosis?

    Model answer

    A carrier of cystic fibrosis has one faulty copy of the gene and one working copy, so the person has no symptoms but can pass the fault on.

  5. 5

    How does cystic fibrosis affect the lungs?

    Model answer

    Cystic fibrosis makes mucus thick and sticky, so the airways clog and trap bacteria, causing repeated chest infections and progressive lung damage.

  6. 6

    How does cystic fibrosis affect digestion?

    Model answer

    Thick mucus blocks the ducts of the pancreas, so digestive enzymes cannot reach the gut and food is poorly absorbed.

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