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Core Studies: Biological Area

Maguire et al. (2000) taxi drivers: MRI analysis and results

  • 3 things to know
  • Component 02

Overview

Recall questions on how Maguire et al. examined the brains using MRI, voxel-based morphometry and pixel counting, blinding, and the findings for posterior and anterior hippocampi, total volume and years of taxi driving experience.

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Process

Was total hippocampal volume different between the groups?

Key term

Describe the second analysis technique.

Key term

How were the brains examined?

Questions from this subtopic

Each one with the model answer underneath.

  1. 1

    How were the brains examined?

    Model answer

    Every participant had a structural magnetic resonance imaging scan of the whole brain.

  2. 2

    What does voxel-based morphometry measure?

    Model answer

    It is an automated technique that compares the density of grey matter across the whole brain between two groups, so differences can be found without deciding in advance where to look.

  3. 3

    Describe the second analysis technique.

    Model answer

    Pixel counting was used, in which hippocampal volume was measured by hand from cross-sectional slices divided into anterior, body and posterior regions.

  4. 4

    Why was the person doing the pixel counting kept unaware of group membership?

    Model answer

    So that expectations about which scans belonged to taxi drivers could not influence the measurements, which removes researcher bias.

  5. 5

    What was found in the posterior hippocampi?

    Model answer

    The taxi drivers had significantly more grey matter there than the controls, on both sides of the brain.

  6. 6

    What was found in the anterior hippocampi?

    Model answer

    The controls had significantly more grey matter there than the taxi drivers.

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